July 28, 2017

Brandeis Science: Exploring Active Matter

Brandeis University, despite its youth, has become known as a prestigious research institution. In the Carl J. Shapiro Science Center students are immersed into the world of science in the biology and chemistry labs. In the same building, and spanning 3 floors of research labs, researchers sharpen their minds and curiosity on the cutting-edge questions of the day. Today’s question concerns active matter.

Active matter is a relatively new field of study which has only attracted serious attention in the past 20 years. The term “active matter” refers to groups of individuals that act independently, but whose respective movements collectively cause much bigger motions. Examples of active matter most people are probably familiar with are large flocks of birds that seem to create a swarm-like cloud or a large school of fish. But these independent actors could be much simpler such as individual cells, molecules or, in the case studied at Brandeis, specific cell structures. While the concept of active matter may sound like something the general public has no reason to care about, the potential applications with real world consequences could significantly improve the way we live.

In 2008 Brandeis became one of seventeen major research universities to take part in an initiative by the National Science Foundation to develop new machines and materials. The university was granted $20 million for 12 years of research and labeled as a Material Research Science and Engineering Center. These institutions focus on studying active matter with Brandeis’s team consisting of 16 scientists from physics, biology and mathematical backgrounds.

The minds leading the charge in the Brandeis labs are Seth Fraden PhD ’87, Zvonimir Dogic ’95, PhD ’01, Tim Sanchez PhD ’12, and Aparna Baskaran. Fraden, a Brandeis physics professor, and Dogic, a Brandeis associate physics professor, run the lab and have emerged at the head active matter exploration effort. They have a history of collaborating on soft matter – matter that is between a liquid and a solid, such as gels — research where they use innovative methods to combine biological material with inanimate matter.

While some scientists may study active matter on large scales, Fraden and Dogic study it on the cellular level. More precisely, on the cell’s structural level. They have been examining microtubules, tiny hollow tubes that provide a cell’s structural integrity, from cow neurons. Microtubules also aid the delivery system within the cell by allowing kinesin, a protein that delivers nutrients and genetic material, to “walk” around the cell powered by adenosine triphosphate (ATP). These microtubules expand and contract individually, but when the movements are taken collectively they allow the cell to stretch, shrink and change shape in response to its environment.

Sanchez, while working as a postdoc fellow under Dogic, discovered that by adding a polyethylene glycol to the microtubule-kinesin-ATP mix the microtubules bunched together and began moving like cilia. Motile cilia are the hair-like structures on the outside of some cells that whip back and forth. In nature, cilia are made from hundreds of proteins and move much more rapidly than the ones Dogic’s team created. While these faux-cilia are no replacement for naturally occurring cilia, they could eventually be used in new medication delivery systems among other potential applications.

The discovery of the faux-cilia led to further experimentation with the microtubules regarding how they interacted with their environment. In collaboration with postdoc Kan-ta Wu, a Brandeis physics lecturer, the team discovered not only that a certain shaped container cause the microtubule concoction to move by itself, but when placed on a flat surface it would flow by itself as well. Self-flowing liquid is fascinating for several reasons. It is something straight from science-fiction, reminiscent of 1958’s the Blob, and has potential for multiple applications such as a replacement or supplement to scenarios where a pump is limiting. One example is moving oil across large areas.

Aparna Baskaran, a physics associate professor at Brandeis, bridges the gap between the lab and real world application. She takes on the task of figuring out the math within Dogic’s team’s trial-and-error approach by trying to create mathematical models predicting the matter’s movement. Without her work the uses of a self-moving liquid can’t be fully realized until we are sure it won’t take on Blob-like tendencies. Developing models to predict active matter movements are made especially difficult by the number of individual actors and that there is no distinctive leader, as seen in the case with birds called Starlings. If Baskaran and other active matter scientists are successful, we could be entering an era of self-moving, self-repairing material in both the commercial and medical industries. Imagine a world where 3D printed transplant organs, a technology actually in development, could repair and maintain themselves.

The science happening in Brandeis labs is absolutely ground breaking, but likely would not be possible without the minds and resources Brandeis provides. Among the schools involved with the National Science Foundation and active matter research, Brandeis is especially well suited to this research due to the interdisciplinary requirements. The university values academic diversity and encourages interdisciplinary study and cooperation. Without scientists from such diverse fields and knowledge, and the top-notch resources provided by university, this research would be incomplete and our world would be worse off for it.

Since 1948 Brandeis National Committee has supported the Brandeis sciences in addition to the libraries and student scholarships. Brandeis strives to provide the proper support and resources necessary for bright minds to thrive. Join us in the world’s largest friends-of-a-library network to help ensure Brandeis remains an institution of inspiration for scientists, scholars, future leaders, and artists.

Read the full article by Lawrence Goodwin in Brandeis Magazine here

Watch a video of microtubules in action at BrandeisNOW here

Brandeis News: Brandeis Receives $50 Million Gift

On Tuesday, June 27th 2017, Brandeis University announced it had received a $50 million bequest from the estate of Rosaline and Marcia Cohn. This gift is significant for several reasons. Since its founding in 1948, this is the first time Brandeis has received a gift of this size in a single donation. As per the wishes of the Cohn family, the money will go towards scholarships for deserving and outstanding students through the Jacob and Rosaline Cohn Endowed Scholarship Fund. This generous gift will allow hundreds of students to pursue their academic aspirations. Perhaps the most remarkable aspect of the gift is that nobody in the Chicago-based Cohn family had a direct connection to Brandeis University.

In 1951, Rosaline Cohn became a life member of the then Chicago chapter of the Brandeis National Committee. Her interest and support of the school, inspired by the first president Abram Sachar, continued to flourish. In true BNC fashion, Rosaline and her husband Jacob, who the fund is named for, chose to support Brandeis because of its values and commitment to academic excellence and openness. The future the Cohn family envisioned is filled with students that will carry Brandeis’ values with them as they go on to do great things. It is with these values in mind that the Brandeis National Committee would like to extend our thanks and deepest appreciation to our many members who did not attend Brandeis, but understand the unique experiences an institution of its caliber provides.

Read the full story on BrandeisNOW.

To continue supporting the Brandeis National Committee, libraries, student scholarships and scientific research visit BNC giving.

 

 

 

Cocktails and Conversation

May 18, 2017 
5 p.m. – 7 p.m.
At the home of Marsha Stoller  (5th Avenue and E. 93rd St) 

Please join us for this special gathering of Brandeis alumni, BNC members, and friends for refreshments and a brief presentation by James Gibert, director of planned giving, and M’Lissa Brennan, director of strategy and development. You will learn about creative gift options that provide tax advantages today, life income gifts, as well as future gifts that will cost you nothing now.

This is not a fundraiser — it is an opportunity for you to learn about ways you can benefit and also meet the future needs of Brandeis. Both James and M’Lissa will be available to answer any questions you may have.

RSVP to M’Lissa Brennan by May 15 via email at mlissa@brandeis.edu or call 781-736-4178.

 

Apples to Apples: Just an Illusion

University on Wheels with Professor Don Katz for March 31 in New York City

New York-area Brandeis National Committee members and friends are invited to attend a seminar on Friday, March 31st with Professor Don Katz, who will discuss our sensory brain in his lecture, “Apples to Apples: Just an Illusion.”
People are comfortable in the belief that their sensory systems tell them what is out there in the world. An apple looks like an apple and tastes like an apple, and so we know it’s an apple. In reality, however, this belief  while comforting) is misguided: The information we get from our eyes and tongue is, in fact, highly ambiguous. Far from reporting “what’s out there,” the job of our sensory brain is to guess what’s out there, a job that it performs by putting together as many different sources of ambiguous information as it can.
Professor Katz will show the sensory process in action, demonstrating how easy it is to change what something tastes like and even looks like. These demonstrations are not merely parlor tricks – what they reveal is that illusions, which we like to think represent our sensory systems malfunctioning, are in fact the very basis of perception.
The event, will be held at 10:30 AM at the Barbizon Condominiums, 3rd Fl. 140 E.63 Street.
Admission is $15 per person, payable to BNC, to Shelley Greene, 165 E. 72 St. #2K, NY, NY 10021.

Good Housekeeping Institute Tour and Lunch

How does the Good Housekeeping test products? Come visit their labs, meet their experts, to learn how their engineers, chemists, textile professionals, and other scientists evaluate thousands of products each year, from vacuums to cosmetics to swimwear and more. Tour their test kitchens (where every Good Housekeeping recipe is triple tested), meet with their nutrition department to learn how they assess if a food lives up to its claims, and visit the famous Good Housekeeping dining room, which has been host to dozens of presidents, first ladies, celebrities, and other famous figures. After the tour, we will have lunch across the street at the organic Bareburger Restaurant.

March 10th- 11:15 am

Limited to 20 members at $46 per person

For more information, contact Linda M Schain, lmschain@gmail.com

 

Living Room Learning: Ruth Brayer, Handwriting Analyst

Ruth Brayer, handwriting analyst, certified graphologist and forensic expert witness qualified by the Supreme Court of the State of New York, will speak to us about how handwriting reveals our personality traits. As a past president of the National Speakers Association (New York chapter) and a former Adjunct Professor at Hofstra University, she has many years of experience, and we look forward to a fascinating afternoon.

This event is limited to members only, and costs $30 per person. Please contact Phyllis Chasin at phylchasin@aol.com, for more information.

Backstage at the Met

We will meet at the south end of the lobby at the Metropolitan Opera House at Lincoln Center. Join us in going behind the scenes for an exclusive look at what it takes to make operatic magic. Our tour includes visits to the scenic and carpentry shops, rehearsal rooms, costume and wig departments, dressing rooms and stage areas. The Metropolitan Opera House building is a work of art within itself, displaying costumes and photos throughout its hallways and filled with memorabilia of past performances.

Note: There will be long periods of standing, walking and stairs during this 75 minute tour. Totes and shopping bags will not be allowed on the tour, so please carry small handbags only. There are no checkroom facilities or restrooms available during the tour.

February 28th- 2:30 pm

For further information contact Maxine Schweitzer at mjrs141@gmail.com

$35 per person. Limited to 30 people

“Brandeis and You” Brunch

If you know anyone who may be interested in joining our chapter, bring them to our opening Membership Brunch! Come and eat delicious food with us, and get to know more about BNC’s vibrant history, the exciting events and the study groups we have planned! There are so many more to choose from this time.

We have a guest speaker: Susan L. Schulman, “True and Dishy Tales from a Theater Press Agent” As one of Broadway’s best press agent, Susan L. Schulman has worked with some of the theatre’s most talented and creative people — who sometimes behaved badly and often with astonishing grace – as they struggled to create theater magic. She turns the spotlight on what goes on behind the show curtain, sharing true tales of her life in the theater. Make your reservation now by sending your $25 check, payable to BNC, to Pat Glickman, 301 East 48th Street, #15F, New York 10017. For further information, call Pat 212-486-3976 or Francoise 212-787-0811

If your guest joins BNC by October 1st, 2016, you will be entitled to a FREE full year (8 sessions) of Study groups.

Annual Book and Author Luncheon

Join us at The Yale Club, The Grand Ballroom, 50 Vanderbilt Avenue on November 7th, 2016, for our annual Book and Author Luncheon!

Invitations will be sent out at the end of summer, and we have some exciting authors presenting their dynamic work!

Kati Marton is the author of True Believer: Stalin’s Last American Spy; Enemies of the People: My Family’s Journey to America, a National Book Critics Circle Award finalist; Paris – A Love Story; The Great Escape: Nine Jews Who Fled Hitler and Changed the World; Hidden Power: Presidential Marriages That Shaped Our History; Wallenberg; The Polk Conspiracy; A Death in Jerusalem; and An American Woman. She is an award-winning former NPR and ABC News correspondent and lives in New York City.

Letty Cottin Pogrebin, a Brandeis graduate, is an award-winning writer, lecturer, and founding editor of Ms. Magazine. She is the author of eleven books, including her most recent title Single Jewish Male Seeking Soul Mate, as well as How to Be a Friend to a Friend Who’s Sick and Deborah, Golda and Me. Her numerous articles have been published in The New York Times and the Washington Post, among other publications. Ms. Pogrebin is a leader in many social justice causes. She is on the board of Brandeis University’s Women’s, Gender, and Sexuality Studies Program.

Michael Riedel is the theater columnist for The New York Post and co-host of Theater Talk on PBS. His book Razzle Dazzle: The Battle for Broadway won the 2015 Marfield Prize from the Arts Club of Washington. He appears regularly on the Imus in the Morning program, The Mark Simone Show, The Mike Gallagher Show, and Fox News’ Red Eye. Mr. Riedel lives in New York City. He is a graduate of Columbia University.

Stephen M. Silverman author of The Catskills: Its History and How It Changed America is a twenty-year veteran of Time Inc. and was the first editor of People.com. His books include biographies of the filmmakers David Lean and Stanley Donen, and his work has appeared in Esquire, Harper’s Bazaar, The New York Times, The Times of London, Vogue, and The Washington Post. He lives in New York City.

All event proceeds will go to the BNC Scholarship Campaign, and we encourage everyone to attend!

Friedberg Announced as BNC National President

Madalyn Friedberg, from the Central Westchester chapter, who has served as national vice president of fundraising for the past year, succeeded Barbara Sander as the Brandeis National Committee’s national president on July 1. Madalyn joined the BNC in 1973, and will serve as a leader for the organization and its 41 chapters.

Friedberg joined the BNC at the urging of a friend. A mother of three young children, she was seeking a group of like-minded lifelong learners. She knew about Brandeis University because her father, David Felix, had been friendly with Lawrence Wien, the founder of Brandeis’ Wien International Scholarship Program.

“I liked the BNC women right away,” Friedberg says. “I remember the women didn’t ask what my husband did for a living or how many children I had. They cared about who I was.”

As treasurer of the Central Westchester chapter for many years, she knows the financial advantages of establishing a charitable gift annuity for those interested in supporting the university. In 2015, Friedberg and her husband, Stephen, established a generous charitable gift annuity, planning to create another one this year.

“The premise on which the university was founded is very important to us,” Madalyn says. “Brandeis opened a whole world to people who needed an education. We want to do what we can to support Brandeis.”

http://www.brandeis.edu/magazine/2016/summer/imprint.html

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