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Insights on online learning, tips for finding balance, and news and updates from Brandeis GPS

Tag: Bioinformatics (page 2 of 2)

SPOTLIGHT ON JOBS: Merck (several positions)

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Members of the Brandeis GPS Community may submit job postings from within their industries to advertise exclusively to our community. This is a great way to further connect and seek out opportunities as they come up. If you are interested in posting an opportunity, please complete the following form found here.

WhereMerck & Co. Inc, Kenilworth, NJ.

About: Merck & Co. Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us. Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career..

Positions:

Principal Scientist, Target & Pathway Biology – Cardiometabolics

We are seeking an experienced laboratory scientist with expertise in human genetics and cardiometabolic disease biology to join Target and Pathway Biology group within the department of Genetics & Pharmacogenomics (GpGx) at MRL Boston.  Our mission in GpGx is to leverage human genetics and cutting edge molecular biology technologies to identify and functionally validate novel targets and pathways for therapeutic intervention. The successful candidate will lead a team of biologists providing experimental validation of potential drug candidates.

Principal Scientist, Target & Pathway Biology – Immunology

We are seeking an experienced laboratory scientist with expertise in human genetics and immunological disease biology to join Target and Pathway Biology group within the department of Genetics & Pharmacogenomics (GpGx) at MRL Boston.  Our mission in GpGx is to leverage human genetics and cutting edge molecular biology technologies to identify and functionally validate novel targets and pathways for therapeutic intervention. The successful candidate will lead a team of biologists providing experimental validation of potential drug candidates.

Principal Scientist, Target & Pathway Biology – Neuroscience

We are seeking an experienced laboratory scientist with expertise in human genetics and neuroscience disease biology to join Target and Pathway Biology group within the department of Genetics & Pharmacogenomics (GpGx) at MRL Boston.  Our mission in GpGx is to leverage human genetics and cutting edge molecular biology technologies to identify and functionally validate novel targets and pathways for therapeutic intervention. The successful candidate will lead a team of biologists providing experimental validation of potential drug candidates.

Computational Biologist, Biologics, Genetics and Informatics IT (BGIx),

The Merck Biologics, Genetics and Informatics IT department (BGIx) works closely with the Genetics and Pharmacogenomics (GpGx) group in Merck Research Labs (MRL) to develop novel therapies grounded in human genetics, including the identification of new therapeutic targets and the development of clinical genomic biomarkers. The BGIx group seeks to significantly expand its team, by adding three bioinformatics and computational biology experts to support expanding research efforts in this area.
Specifically, we seek individuals to partner with GpGx and assist with:
1) analysis of large-scale human genome sequencing efforts for target discovery,
2) design and analysis of custom sequencing experiments to support target validation (single-cell sequencing, long-read technologies, multiplex screening approaches, etc.)
3) integration and analysis of data from diverse sources including microarray expression and genotyping, NGS-based experiments, flow cytometry, and clinical endpoints, and 4) management of genomic and genetic data from pre-clinical and clinical programs.

Interested candidates should apply using the careers website through the MSD Career Firm conducting the search for these positions

Make sure to reference seeing this position through the Brandeis GPS job spotlight post.

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SPOTLIGHT ON JOBS: BERG, LLC

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SPOTLIGHT ON JOBS

Members of the Brandeis GPS Community may submit job postings from within their industries to advertise exclusively to our community. This is a great way to further connect and seek out opportunities as they come up. If you are interested in posting an opportunity, please complete the following form found here.

Where: BERG Health, LLC Framingham, MA

About: Berg focuses our research on understanding how alterations in metabolism relate to disease onset. The company has a deep pipeline of early-stage technologies in CNS diseases and metabolic diseases that complement its late-stage clinical trial activity in cancer and prevention of chemotoxicity.  Armed with use of the Interrogative Biology™ discovery platform that translates biological output into viable therapeutics and a robust biomarker library, Berg is poised to realize its pursuit of a healthier tomorrow

Position: Data Scientist–Healthcare Analytics

The Healthcare Analytics team is seeking a highly motivated, meticulous and detail-oriented individual for a rapidly growing multi-disciplinary team. The candidate will be instrumental in analyzing and making inferences from healthcare big data and must be goal oriented and should have strong background in statistics, epidemiology and possess some programming skills. The candidate should also be a quick learner, extremely flexible and able to adapt to needs of the project.

Responsibilities:

  • Perform meticulous and well thought-out data analysis for hypothesis testing on healthcare big data.
  • Development and execution of data analysis protocols to support company’s discovery pipeline.
  • Detailed documentation of data analysis methods and findings.
  • Presentation of scientific results internally and externally.

Requirements:

  • Requires a Ph.D. or Masters with 5+ years of relevant experience in Statistics, Epidemiology, Public Health, Data Science or related field.
  • Strong skills in statistics and study design.
  • Experience working with healthcare claims, pharmacy and EMR data is a highly desirable.
  • Proficiency in R, MySQL and Perl is preferred.
  • Proven ability to find creative, practical solutions to complex problems.
  • Excellent communication and interpersonal skills combined with superior and proven track record of technical and organizational skills.
  • Must be able to work in team-oriented environment and demonstrate attention to detail and record keeping.

 

Anyone interested in applying to this position may send their resume, cover letter and three references to hr-68931@berghealth.com.

May sure to reference seeing this position through the Brandeis GPS job spotlight post.

 

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SPOTLIGHT ON JOBS: Bioinformatician/Microbiologist at IHRC, Inc.

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SPOTLIGHT ON JOBS

Members of the Brandeis GPS Community may submit job postings from within their industries to advertise exclusively to our community. This is a great way to further connect and seek out opportunities as they come up. If you are interested in posting an opportunity, please complete the following form found here.

Title:  Bioinformatician/Microbiologist, Full Time–assigned to the Enteric Diseases Laboratory Branch (EDLB) within the Division of Foodborne, Waterborne, and Environmental Diseases (DFWED) at the US Centers for Disease Control and Prevention (CDC)

Where:  IHRC, Inc.– 2 Ravinia Drive-Suite 1750, Atlanta, GA 30346

About:   IHRC, Inc. provides scientific, information management and administrative program support to various Centers, Institutes and Offices of the Centers for Disease Control and Prevention (CDC) under several contracts.

 

 
   MAJOR DUTIES AND RESPONSIBILITIES:

•Work very closely with EDLB Bioinformaticians to process raw sequence data produced by Sanger and NGS, to identify, characterize and annotate genes found in sequence data, perform evolutionary and phylogenetic studies of sequence data, identify unique regions of pathogen genomes for use as targets in molecular diagnostic assays, and design oligonucleotide primers/probes for use in sequencing projects and foodborne bacteria pathogen detection assays.

•Analyze genetic sequencing data utilizing new methodologies or existing techniques that have been properly revised and validated.

•Develop, evaluate, and validate bioinformatics tools to establish correlations between unique genetic markers (extracted from whole genome sequences) and the species/serotype of foodborne bacterial pathogens.

•Perform standard molecular biology techniques, including but not limited to, manual and automated nucleic acid extraction, Polymerase Chain Reaction (PCR), Sanger sequencing, and Next Generation Sequencing (NGS) to develop and validate schemes to rapidly identify and subtype bacterial pathogens from complex matrices.

•Evaluate novel approaches to address human and commensal bacterial DNA in disease state stool, including clutter mitigation.

•Assist with the establishment of procedures for Quality Assurance (QA) and Quality Control (QC) of sequence data analysis in the context of this project.

•Assist in implementation of the developed assays by training laboratorians from state, county and local public health laboratories.

•Prepare reports, charts, graphs, and presentations as required.

 

   Minimum Qualifications and Technical Requirements:

•Must have successfully completed a full 4-years course of study in an accredited college or university leading to a bachelor’s and a higher degree (Master’s or Ph.D.) with at least 24 semester hours in mathematics, statistics, bioinformatics, or informatics and 24 semester hours molecular biology, microbiology, or genetics.

•The successful candidate will have a 2-3 years demonstrated experience with bioinformatics, bioinformatics analytical tools, microbiology, and molecular biology laboratory techniques.

•Be proficient in the use of various whole genome sequence laboratory procedures.

•Be proficient in the analysis, assembly, and annotation of genomic data from a variety of sequencing platforms such as Illumina and PacBio.

•Have strong interpersonal skills since the work is to occur in a multidisciplinary team environment and extensive interaction with people across CDC and external partners is required.

•Have strong written and oral presentation skills.

•Be capable of developing and executing research tasks independently.

•REQUIRED experience with Illumina sequencing technology, molecular biology assay design, UNIX (BASH scripting) and cluster computing (SGE); experience with coding in PERL and/or PYTHON; experience with relational databases (i.e. MySQL, Microsoft SQL server), Microsoft Excel, Microsoft Word.

•DESIRABLE experience with Microsoft Access, SAS, experience with metagenomics databases such as Kraken and MetaPhlAn, prior work with bacterial genome sequencing and analysis.

•The candidate must possess excellent oral and written communication

 

Contact Person for Job Opportunity:

Michael Astwood

678-615-3220

mastwood@ihrc.com

 

To apply for this position visit www.ihrc.com/careers . If already on the IHRC website, click on the job you are interested in and click on the apply button at the bottom of the page.

IHRC, Inc. is an equal opportunity and affirmative action employer. It is the policy of IHRC, Inc. to provide equal employment opportunities without regard to race, color, religion, sex, national origin, age, veteran or disability status and to take affirmative action in accordance with applicable laws and Executive Orders.

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SPOTLIGHT ON JOBS: Stem Cell Bioinformatics Faculty Search

Welcome to the first

SPOTLIGHT ON JOBS!

Members of the Brandeis GPS Community may submit job postings from within their industries to advertise exclusively to our community. This is a great way to further connect and seek out opportunities as they come up. If you are interested in posting an opportunity, please complete the following form found here. To stay in touch and receive further SPOTLIGHTS, make sure to subscribe to our blog

Title: Assistant Professor in the University Tenure Line (UTL)

Where: Institute for Stem Cell Biology and Regenerative Medicine in Stanford University, to be identified as the optimal home department of the successful candidate.

Qualifications: Interested in candidates who have a doctoral degree in computer science, electrical engineering, bioinformatics or related field and who have research interests in clinical or translational informatics, bioinformatics, or related subdisciplines, and who have or will develop an independent research program in the computational sciences. The predominant criterion for appointment in the University Tenure Line is a major commitment to research and teaching. The successful candidate will conduct a vigorous, independent research program, teach in the classroom, and advise students in any of a number of graduate programs in computational sciences. Faculty members appointed as Assistant Professors will have completed one or two years of postdoctoral research experience. Their accomplishments during graduate and postgraduate training should already have stamped them as creative and promising investigators. Preference will be given to candidates who have experience in developing novel analytical tools to analyze the cellular composition of organs and/or tissues and who can complement and enhance existing strengths in stem cell biology, cancer biology, developmental biology, bioinformatics, and bioengineering within the Institute and the University.

We expect the successful candidate to establish an innovative research program studying fundamental stem cell biology. Responsibilities include teaching graduate students and research-oriented medical students in an area that would complement the Institute’s existing strengths.

The activities of the Division/Department are diverse and include basic, translational and clinical applications in embryonic stem cells, reprogramming, cancer stem cells and adult stem cells. The stem cell biology and regenerative medicine activities offer unique opportunities for the successful candidate to build a strong program of independent research complemented by collaborative efforts across different departments.

How to Apply: Interested candidates should send a copy of their curriculum vitae, a brief letter outlining their interests and the names of three references to:

Dr. Michael F. Clarke
Chair, Stem Cell Computation Search Committee
Institute for Stem Cell Biology and Regenerative Medicine
Lorry Lokey Stem Cell Research Building, Room G2021A
265 Campus Drive West
Stanford, CA 94305-5461

Stanford University is an equal opportunity employer and is committed to increasing the diversity of its faculty. It welcomes nominations of and applications from women, members of minority groups, protected veterans and individuals with disabilities, as well as from others who would bring additional dimensions to the university’s research, teaching and clinical missions.

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Brandeis GPS Commencement Wrap-Up

Written by: Kelsey Whitaker, A Senior at Brandeis University

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Amyntrah Maxwell & Rabb VP Karen Muncaster

On May 17th, to the sounds of “Pomp and Circumstance”, the Rabb School of Graduate Professional Studies‘ class of 2015 donned their caps and gowns and received their diplomas. The ceremony awarded Master’s degrees in various fields  including: Bioinformatics, Health and Medical Informatics, Information SecurityIT ManagementProject & Program Management and Software Engineering. Students sat proudly and  enjoyed the student and main commencement speaker’s words of wisdom for their future.   As working professionals in their respective fields, each degree recipient juggled work, school, and personal  matters in order to earn their master’s degree.

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Student speaker, Louis Rosa III

The student speaker for the day was Louis Rosa III, who earned his Doctor of Medicine from Georgetown University’s School of Medicine and has over 30 years of experience in the fields of neurosurgery and radiation therapy. However, the day of commencement Rosa walked out with a newly earned diploma in Health and Medical Informatics. After all of his experience, why did Rosa pursue his degree from Brandeis GPS? “No matter how many patients I saw, I couldn’t have enough of an impact,” Rosa explained. Rosa went on to explain the impact his new degree would have on his career and his life.

The main Commencement speaker, Curtis H. Tearte, is a 1973 Brandeis graduate and also a  current Board of Trustees member. Tearte has vast experience in technology and business as former director, vice president and general manager of IBM “My experience at Brandeis exponentially changed the arc of my life,” he explained to the graduates. Tearte is also the founder of Tearte Associates, a firm dedicated to seeking out students with academic potential to become Tearte Scholars through his Family Foundation. His advice to the graduates was, “Keep putting out good and it will come back to us tenfold in unexpected ways.”

Commencement speaker, Curtis H. Tearte

In addition to the speakers, the Outstanding Teacher Award Recipient was presented to Leanne Bateman. Teaching at Brandeis since 2007, Bateman serves as Academic Program Chair and a faculty member for Project and Program Management and Strategic Analytics. Congrats, Leanne!

Congratulations to the 2015 graduates! You did it! Good luck in all your future plans and endeavors.

Want to see the live stream of commencement? You’re in luck! Watch it here.

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Brandeis expands online course offerings with Learning Analytics graduate certificate

New fall program combines data analysis with the expanding field of online learning

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Brandeis University’s Graduate Professional Studies division (GPS) will launch a fully-online graduate certificate program in Learning Analytics in September 2015, the university announced today.

Designed to be completed in 1.5 years or less, the program is for professionals with strong backgrounds in education, instructional design, or institutional research. Cross-disciplinary in nature, the certificate will provide students with the foundational tool sets and theory of business intelligence and data analysis. These skillsets are necessary for evaluating the effectiveness of courses, programs and instruction, and prepare students to fill a highly in-demand skills gap in a burgeoning job market.

“As the learning analytics field continues to evolve, it is more important than ever before to use the technology and data we have available to us to understand and, ultimately, enhance the learning experience,” said Brian Salerno, director of Online Learning and Instructional Design at Brandeis GPS.

The five-course, 15-credit certificate program draws heavily from two existing Brandeis GPS master’s degrees: Instructional Design and Technology and Strategic Analytics. Applicants are expected to possess a post-graduate degree in a related field as well as three years of relevant work experience.

In addition to the new Learning Analytics certificate, Brandeis GPS offers eight fully online part-time master’s degrees, including Strategic Analytics, Bioinformatics, Health and Medical Informatics, Instructional Design & Technology, and Software Engineering. All Brandeis GPS programs are asynchronous, providing students with a flexible and convenient approach to completing their degree.

Students interested in applying to the Learning Analytics certificate program should complete their application by Aug. 11, 2015. Students also have the opportunity to take a course prior to applying for admission. Registration for the summer 2015 term opened on April 14, with courses beginning May 20. For more information about Brandeis GPS, please visit www.brandeis.edu/gps.

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Is Healthcare the Next Frontier for Big Data?

By:– Custom Content Coordinator, BostInno

The health care industry has always been at the center of emerging technology as a leader in the research and application of advanced sciences. Now, more than ever, the industry is on the edge of an innovation boom. Health care information technology possesses vast potential for advancement, making the field fertile ground for game-changing innovation and the next great frontier for big data.

The use of electronic health records (EHR), electronic prescribing, and digital imaging by health care providers has exploded in recent years, Health Affairs reports and the global program-hero-itm1health information exchange (HIE) market is projected to grow nearly ten percent per year, reaching $878 million in 2018, according to Healthcare Informatics.

But despite massive growth, health care IT faces a number of barriers slowing advancement.

When it comes to health information technologies, demand is outpacing delivery. Users desire higher levels of performance beyond the capacity of current IT solutions.

“Providers certainly want to do things that vendor technology doesn’t allow right now,” Micky Tripathi, Ph.D., CEO of the Massachusetts eHealth Collaborative (MAeHC), said to Healthcare Informatics.

One reason technology is lagging is health care IT systems are independently developed and operated. Rather than one massive network, there are numerous “small shops developing unique products at high cost with no one achieving significant economies of scale or scope,” Health Affairs reported. As a result, innovations are isolated, progress is siloed, and technology cannot meaningfully advance.

To deliver the highest quality of care, the health care community must unite disparate systems in a centralized database. But, this is easier said than done. The industry must be sure to maintain the highest standards of security complying with Health Insurance Portability and Accountability Act of 1996 (HIPAA). Medizin

As a result, the health care IT industry currently faces a crucial challenge: devise an overarching system that guarantees security, sustainability, and scale.

The key to unlocking solutions is Big Data are the informaticians who translate mountains of statistics into meaningful healthcare IT applications.

“The growing role of information technology within health-care delivery has created the need to deepen the pool of informaticians who can help organizations maximize the effectiveness of their investment in information technology—and in so doing maximize impact on safety, quality, effectiveness, and efficiency of care,” the American Medical Informatics Association noted. The future of health care hinges on the ability to connect the big data dots and apply insights to a creating and practicing a smart IT strategy.

Organizations have thrown themselves into the big data trenches to innovate solutions to the problem facing their industry. Ninety-five percent of healthcare CEOs said they were exploring better ways to harness and manage big data, a PricewaterhouseCoopers study reported. With the commitment of the health care community, plus the right talent and resources, industry-advancing innovations won’t be far behind.

Health care is indisputably the next great frontier for big data. How we seek, receive, and pay for health care is poised to fundamentally change and health care informaticians will be leading the evolution.

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My Journey as an “Adult” Student

adult-studentOk so here I am, I was told at work that I need to take a course for professional development…really? I already have my master’s degree, I thought I was done with school. Although I did always think that I would be one of those people that was a lifelong student. It has been 10, 11, 12 years maybe since I last took a “real” course. You know what happens, life….marriage, kids, house, etc. etc. all the excuses, I mean, reasons why I haven’t taken any courses since my master’s degree. I must admit this pit in my stomach may be fear or is it excitement? How can I fit a 10-week, 3-graduate credits, minimum 3 posting a week course into my 2 kids (4yr old and 1 yr old), husband, house, full-time job, 2+ hour commute schedule? As I sit hear waiting for fall registration to open, I think the pit in my stomach is excitement and not fear. I’m going to learn again.

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