Grad Student
Volen Center for Complex Systems
Brandeis University,
Mailstop 013
415 South Street
Waltham MA 02454
USA
Tel: (781) 736-3134
Fax: (781) 736-3142
Education:
B.A., Hampshire College
M.Ed. University of Massachusetts, Amherst
Background: I came to computational neuroscience after teaching high school science for several years.
Research Interests:
I am interested in creating biophysically realistic models of small networks. I search for models which accurately reflect the characteristics of identified pattern generating cells in the crab stomatogastric ganglion. I am interested in understanding how these networks can be robust in the face of changes such as temperature fluctuations.
Current Projects:
I am exploring temperature scaling in models of the STG pacemaker kernel in an attempt to understand the constraints on this scaling required to produce the phase maintenance recorded in vivo.
Publications:
Tang, Goeritz, Caplan, Taylor, Fisek and Marder. Precise temperature compensation of phase in a rhythmic motor pattern. PLoS Biol. 2010 Aug 31;8(8). pii: e1000469 PMCID: PMC2930868 doi: 10.1371/journal.pbio.1000469
Szabo, Caplan, Zoran 2010. Serotonin regulates electrical coupling via modulation of extrajunctional conductance: H-current. Brain Res. 2010 Aug 19;1349:21-31. PMID: 20599836 doi: 10.1016/j.brainres.2010.06.025
Kispersky*, Caplan* and Marder 2012. Increase in Sodium Conductance Decreases Firing Rate and Gain in Model Neurons. J Neurosci 8 August 2012, 32(32) 10995. doi: 10.1523/JNEUROSCI.2045-12.2012
O’Leary T, Williams AH, Caplan JS, Marder E. 2013. Correlations in ion channel expression emerge from homeostatic tuning rules. Proc Natl Acad Sci USA. 2013 July 9;110(28):E2645-54. doi: 10.1073/pnas.1309966110.