Dr. Sonal Shruti

Post-Doctoral Researcher

Volen Center for Complex Systems
Brandeis University,
Mailstop 013
415 South Street
Waltham MA 02454

Tel: (781) 736-3134
Fax: (781) 736-3142

B.Sc, TM Bhagalpur University, 2000

M.Sc, Jawaharlal Nehru Unversity, New Delhi, 2004

Ph.D, Carnegie Mellon University, Pittsburgh, 2010

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1. S Shruti , RL Clem, AL Barth. A seizure-induced gain-of-function in
BK channels is associated with elevated firing activity in neocortical
pyramidal neurons. Neurobiology of Disease, 30(3):323-30, Jun 2008.

2. RC Gerkin, RL Clem, S Shruti, RE Kass, AL Barth. Cortical up state
activity is enhanced after seizures: a quantitative analysis. J Clin
Neurophysiol, 27(6):425-32, Dec 2010.

3. S Shruti, J Urban-Ciecko, JA Fitzpatrick, R Brenner, and MP
Bruchez, and AL Barth. The brain-specific beta4 subunit downregulates
BK channel cell surface expression. PLoS One, Epub Mar 16, 2012

I am interested in studying the molecular and cell biological
mechanisms of plasticity in intrinsic excitability and connectivity of neurons and how such changes affect circuit output.
  • Expression and distribution of innexins in the stomtogastric ganglion (STG) of C. borealis.