Weighing in on CTE diagnosis

We noticed a new paper this week in Brain Research on chronic traumatic encephalopathy (brain damage from repeated blows to the head, which has been all over the news this year) from a Brandeis author, Madeline Engeler ’16, a Biology/HSSP double major.

We reached out to Madeline for the inside scoop, here’s what she told us:

Yes this is my paper. I am so excited it is finally published! […] This research came from the summer of 2014 when I was at the Cleveland Clinic Lerner Research Institute. I was funded through Brandeis’ World of Work fellowship program and I gained credit for my HSSP hands-on experience.
This research came about from some of us in the lab reading papers about post-mortem diagnosis of CTE in NFL players. What was intriguing was that very similar morphologies were seen in the epileptic brain resections we were studying. So we decided to depart from our epileptic brain research and stained these samples with the same antibodies as in the CTE papers. We also obtained NFL brain samples from Dr. Mckee at BU to do our own staining. Our results showed remarkably similar images from the epileptic and CTE brains. This caused us to posit that perhaps the post-mortem diagnosis of CTE is too broad because it encompasses other neurological conditions, such as epilepsy.

You can read the paper for yourself online:

Puvenna V, Engeler M, Banjara M, Brennan C, Schreiber P, Dadas A, Bahrami A, Solanki J, Bandyopadhyay A, Morris JK, Bernick C, Ghosh C, Bazarian JJ, Janigro D. Is phosphorylated tau unique to chronic traumatic encephalopathy? Phosphorylated tau in epileptic brain and chronic traumatic encephalopathy. Brain Res. 2015.

Phi Beta Kappa Elects 51 Division of Science Students

Phi_Beta_Kappa_KeyThe Brandeis chapter of Phi Beta Kappa recently elected 97 new members. Of the 97, at least 51 undergraduate students are majors in the Division of Science (Biochemistry, Biological Physics, Biology, Chemistry, Computer Science, Mathematics, Neuroscience, Physics and Psychology).

Congratulations to the following new Phi Beta Kappa members from the Division of Science:

Biochemistry

Malia Barbra McAvoy
Yehonatan Otzar Meschede-Krasa
Juhee Park
Lior Rozhansky
Hanchen Zhao (double major with Chemistry)

Biological Physics

Abigail Rose Knecht

Biology

Ignatius Ang
Zachary Ian Fried
Jenna Leah Kahane
Ariel Jennifer Katz
Yang Li
Yixuan Liao
Alice Yuan Meng
Khang Vi Nguyen (double major with Chemistry)
Danielle Marie Quintin
Sarah Shin

Chemistry

Khang Vi Nguyen (double major with Biology)
Soobyung Park
Noam Isaac Saper
Hanchen Zhao (double major with Biochemistry)

Computer Science

Kenneth William Foner
Huy Quang Mai
Grady Berry Ward (double major in Mathematics)

Mathematics

Cameron Zhang Fen
Trevor Weiss Kafka
Linda Li
Huy Quang Mai
Stefan Stanojevic
Zhengyang Zhou
Daniel Jackson Kutner (double major in Physics)
Murielle Claire Tugendhaft
Grady Berry Ward (double major in Computer Science)

Neuroscience

Jessica Allison Haley (double major with Psychology)
Kiera Gillian Sarill (double major with Psychology)

 

Physics

Wei Zhong Goh
Stefan Stanojevic
Daniel Jackson Kutner

Psychology

Kyra Jordana Borenstein
Hannah Dvorah Caldwell
Nicole Danielle Cardona
Avi David Cohen
Annie Cui
Jason Michael Desimone
Emily Rose Friedman
Jonathan David Gilman
Clara Emily Gray
Cecilie Gromada
Sarah Jessica Hack-Chabot
Jessica Allison Haley (double major with Neuroscience)
Jessica Lynn Lieberman
Danielle Mizrachi
Emily April Mostow
Linda Sue Nakagawa
Talia Michelle Portal
Jenna Louise Rice
Kiera Gillian Sarill (double major with Neuroscience)
Aliza Naomi Shapiro

See full story on BrandeisNow.

Undergraduate Lab Tours Begin

Are you an undergraduate interested in gaining research experience by working in a lab at Brandeis? Not sure how to find a lab to work in?

The Biology Undergraduate Department Representative (UDRs) have created the Lab Tour Program. The first tour was held on Monday, April 13th. Lead by Biology junior, Sarita Biswas ’16, undergraduates toured the Dorothee Kern, Daniel Oprian and Chris Miller labs. Although a Biology major, Sarita has worked in Kern’s Biochemistry lab for nearly a year. During the tour, students were shown lab equipment and specialized research rooms (cold room, autoclave room) in the Volen Center. Throughout the tour, Sarita discussed the research that is being done in the labs.

Following the tour, Rashieda Pugh ’16 (UDR) and Sarita sat down with the students. Sarita discussed the kind of projects that she has worked on in the past year. Both Sarita and Rashieda shared their experiences in finding a suitable lab to work in, how they find a project to work on once in the lab, and the time commitment during the summer and academic year.

Some of the many questions asked:

  • Will there be a someone there to guide me? There is always a graduate student or postdoc mentoring you.
  • How do you find a lab to work in? Review the faculty webpages, find research that interests you and then email the professors. Do not write all the professors a generic email about opportunities in their lab. It’s unlikely to work. Take the time to find out what kind of research goes on in each lab. Target labs in which you have a genuine interest. Be prepared to show up in person and talk intelligently about research projects with the faculty member. Be prepared to emphasize what you have to offer – skills acquired in courses or other jobs, your dedication and willingness to apply yourself, your reliability and punctuality, your ability to communicate clearly and concisely, etc.
  • Is lab research considered an internship? Yes, it is very much like an internship.

Their advice is that there are a lot of labs here at Brandeis and a lot of ways to find rewarding research experience in a lab!

The Lab Tour continues on April 16th.

Rachel Woodruff Promoted to Assistant Professor

Rachel WoodruffRachel Woodruff has been promoted to Assistant Professor of Biology. Rachel joined the Brandeis faculty almost three years ago as an Instructor in Biology. During this time, Rachel has taught several Biology courses for undergraduate and Master’s students and recently guided Biology students as an Undergraduate Advising Head.

James Morris, Associate Professor, recently detailed Rachel’s importance to the Brandeis community:

“Rachel teaches courses for biology majors and non-majors. She regularly teaches Biology 14a-Genetics and Genomics, which is part of the introductory biology sequence. This course is taken by many first and second-year students. In addition, she teaches upper-level courses focusing on DNA damage and repair, as well as cancer, drawing on her research experience on DNA damage in bacteria and yeast. These classes include Biology 150b DNA Research and Mechanisms and Biology 172b Growth Control and Cancer. These seminar-style classes include opportunities to read and interpret scientific papers. She also teaches Biology 101b Molecular Biotechnology for advanced undergraduate and Master’s students, introducing students to techniques in molecular biology and teaching students to write their own research proposals. Finally, she teaches BISC 9b Biology of Cancer for non-majors, introducing this important topic to students in an accessible and engaging way.”

 

JBS Course Focuses on “Food, Lifestyle, and Health”

Elaine Lai, Senior Lecturer in Biology at Brandeis University, will be teaching a Justice Brandeis Semester (JBS) this summer titled Food, Lifestyle, and Health. The class runs from 6/1/2015 to 7/24/2015. The student receives 12 credits upon successful completion of the course. Food, Lifestyle, and Health will provide an immersive academic experience by combining academic training in the classroom with experiential learning in food labs.

The focus of this course will be to explore the link between food and health, specifically focusing on the factors that have lead to our national diabetes epidemic. Some of the issues studied will be the link between poverty and diabetes and diabetes and other chronic health conditions.

Applications for the Justice Brandeis Semester open on February 13, 2015. The application deadline is March 16, 2015.

JBS Offers “Bio-Inspired Design” Course

Maria de Boef Miara, Lecturer in Biology at Brandeis University, will be leading a course titled Bio-Inspired Design this summer (June 1 thru August 7, 2015). Bio-Inspired Design is part of the Justice Brandeis Semester (JBS). JBS combines courses and experiential learning to provide complete, immersive experiences so students can deeply examine a specific area of study.

Bio-Inspired Design is designed for students from a wide spectrum of disciplines, but may be particularly appealing to students in Biology, Biological Physics, Environmental Studies or HSSP areas. This is a 10-week course providing 12 credits.

Students in Bio-Inspired Design will spend the summer working with biologists, engineers and artists in a variety of settings. They will explore intriguing life forms and develop the quantitative tools needed to work at the intersection of form and function.

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