Ratliff, J., Franci, A., Marder, E., and O’Leary, T. (2021). Neuronal oscillator robustness to multiple global perturbations. Biophysical Journal (2021), doi: https://doi.org/10.1016/j.bpj.2021.01.038 [Biophysical Journal]

Powell, D., Haddad, S., Gorur Shandilya, S., and Marder, E. (2021) Coupling between fast and slow oscillator circuits in Cancer borealis is temperature-compensated. eLife 2021;10:e60454 DOI: 10.7554/eLife.60454 [eLife]

Alonso, L., and Marder, E. (2020) Temperature compensation in a small rhythmic circuit. eLife 2020;9:e55470 DOI: 10.7554/eLife.55470 [eLife]

Lily S. HeMara C.P. RueEkaterina O. MorozovaDaniel J. PowellEric J. JamesManaswini KarEve Marder. (2020) Rapid adaptation to elevated extracellular potassium in the pyloric circuit of the Crab, Cancer borealis. Journal of Neurophysiology 2020 123:52075-2089 [Journal of Neurophysiology]

Ori, H., Hazan, H., Marder, E., and Harom, S. (2020) Dynamic clamp constructed phase diagram for the Hodgkin and Huxley model of excitability. 

Northcutt, A., Kick, D., Otopalik, A., Goetz, B., Harris, R., Santin, J., Hofmann, H., Marder, E., and Schulz, D. (2019) Molecular profiling of single neurons of known identity in two ganglia from the crab Cancer borealis. Proc. Natl. Acad. Sci. (USA) 52: 26980-26990. [PNAS]

Gorur-Shandilya, S., Marder, E., and O’Leary, T. (2019) Homeostatic plasticity rules that compensate for cell size are susceptible to channel deletion. [bioRxiv] 

Otopalik, A., Lane, B., Schulz, D., and Marder, E. (2019) Innexin expression in electrically coupled motor circuits. Neuroscience Letters. 695: 19-24. https://doi.org/10.1016/j.neulet.2017.07.016 [Neuroscience Letters]

Kushinsky, D., Morozova, E. and Marder, E. (2019) In vivo recordings of the heart and pyloric rhythms in the crab, Cancer borealis. Journal of Experimental Biology.  222:5. doi: 10.1242/jeb.199190 [Journal of Experimental Biology]

Alonso, L., and Marder, E. (2019) Visualization of currents in neural models with similar behavior and different conductance densities. eLife. 2019; 8: e42722 doi: 10.7554/eLife.42722 [eLife]

Otopalik, Adriane G., Jason Pipkin, and Eve Marder (2019). Neuronal morphologies built for reliable physiology in a rhythmic motor circuit. eLife 2019;8:e41728 [eLife]

Haley, J.A., Hampton, D., and Marder, Eve (2018) Two central pattern generators from the crab, Cancer borealis, respond robustly and differentially to extreme extracellular pH. eLife2018;7:e41877 DOI: 10.7554/eLife.41877 [eLife]

Ratliff, J, Marder, E., and O’Leary, T. (2018) Neural circuit robustness to acute, global physiological perturbations. [bioRxiv]

Haddad, S.A. and Marder, E. (2018) Circuit robustness to temperature perturbation is altered by neuromodulators. Neuron. 100:3;609-623 DOI: https://doi.org/10.1016/j.neuron.2018.08.035 [Neuron]

Rosenbaum, P. and Marder, E. (2018) Graded transmission without action potentials sustains rhythmic activity in some but not all modulators that activate the same current. The Journal of Neuroscience DOI: https://doi.org/10.1523/JNEUROSCI.2632-17.2018 [Journal of Neuroscience]

Bronk, P., Kuklin, E.A., Gorur-Shandilya, S., Liu, C., Wiggin, T.D., Marder, E., and Griffith, L.C. (2018) Regulation of Eag by calcium/calmodulin controls presynaptic excitability in Drosophila. J. Neurophysiol., 119: 1665-1680. [Journal of Neurophysiology]

Otopalik, A.G., Lane, B., Schulz, D.J. and Marder, E. (2017) lnnexin Expression in electrically coupled motor circuits. Neurosci Lett, 10.1016/j.neulet.2017.07.016 [Neuroscience Letters]

Nusbaum, MP, Blitz, DM, Marder, E. (2017). Functional consequences of neuropeptide and small-molecule co-transmission. Nature Reviews Neuroscience18,389 403(2017) doi:10.1038/nrn.2017.56. [PubMed]. 

Otopalik, AG, Goeritz, ML, Sutton, AC, Brookings, T, Guerini, C, and Marder, E. (2017). Sloppy morphological tuning in identified neurons of the crustacean stomatogastric ganglion.eLife 2017;6:e22352 DOI: 10.7554/eLife.22352.[eLife]

Otopalik, AG, Sutton, AC, Banghart, M, and Marder, E. (2017). When complex neuronal structures may not matter.  eLife 2017;6:e23508 DOI: [eLife].

Timothy O’Leary, Eve Marder (2017). Temperature-robust neural function from activity-dependent ion channel regulation. Current Biology. https://doi.org/10.1016/j.cub.2016.08.061. [PubMed].

Marder, E, Gutierrez, G, Nusbaum, MP. (2016). Complicating connectomes: electrical coupling creates parallel pathways and degenerate circuit mechanisms. Developmental Neurobiology. 10.1002/dneu.22410. [PubMed].

Gjorgjieva, J., Drion, G., and Marder, E. (2016) Computational implications of biophysical diversity and multiple timescales in neurons and synapses for circuit performance. Current Opin. Neurobiol, 37: 44-52. https://doi.org/10.1016/j.conb.2015.12.008. [PubMed].

Hamood AW, Marder E (2015). Consequences of acute and long-term removal of neuromodulatory input on the episodic gastric rhythm of the crab, Cancer borealis. J Neurophysiol. doi: 10.1152/jn.00536.2015. [PubMed].

Hamood, A. W., & Marder, E. (2015). Animal-to-Animal Variability in Neuromodulation and Circuit Function. Cold Spring Harbor Symposia on Quantitative Biology. doi:10.1101/sqb.2014.79.024828. [PubMed].

Hamood, AW, Haddad, SA, Otopalik, AG, Rosenbaum, P, & Marder, E. Quantitative Reevaluation of the Effects of Short- and Long-Term Removal of Descending Modulatory Inputs on the Pyloric Rhythm of the Crab, Cancer borealis. eNeuro, 2(1). 2015. doi:10.1523/ENEURO.0058-14.2015. [PubMed].

Marder E, Haddad SA, Goeritz ML, Rosenbaum P, Kispersky T. How can motor systems retain performance over a wide temperature range? Lessons from the crustacean stomatogastric nervous system. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2015 Jan 1. [pubmed] 

Marder E, Goeritz ML, Otopalik AG. Robust circuit rhythms in small circuits arise from variable circuit components and mechanisms. Curr Opin Neurobiol. 2014 Nov 6;31C:156-163. doi: 10.1016/j.conb.2014.10.012. Review. [pubmed]

Shruti S, Schulz DJ, Lett KM, Marder E. Electrical coupling and innexin expression in the stomatogastric ganglion of the crab Cancer borealis. J Neurophysiol. 2014 Dec 1;112(11):2946-58. doi: 10.1152/jn.00536.2014. Epub 2014 Sep 10. [pubmed]

Marder E, O’Leary T, Shruti S. Neuromodulation of circuits with variable parameters: single neurons and small circuits reveal principles of state-dependent and robust neuromodulation. Annu Rev Neurosci. 2014;37:329-46. doi: 10.1146/annurev-neuro-071013-013958. [pubmed]

O’Leary T, Marder E.  Neuroscience: Mapping neural activation onto behavior in an entire animal. Science. 2014 Apr 25;344(6182):372-3. doi: 10.1126/science.1253853. Pubmed

O’Leary T, Williams AH, Franci A, Marder E (2014). Cell Types, Network Homeostasis, and Pathological Compensation from a Biologically Plausible Ion Channel Expression Model. Neuron. 82(4):809-21. [pubmed]

Caplan JS, Williams AH, Marder E (2014). Many parameter sets in a multicompartment model oscillator are robust to temperature perturbations. J Neurosci. 34(14):4963-75. [pubmed]

Soofi W, Goeritz ML, Kispersky TJ, Prinz AA, Marder E, Stein W (2014). Phase maintenance in a rhythmic motor pattern during temperature changes in vivo. J Neurophysiol. [pubmed]

Williams, AH, Hamood, AW, & Marder, E. Neuromodulation in Small Networks. In: D. Jaeger & R. Jung, Encyclopedia of Computational Neuroscience (pp. 1–15). 2014. Springer New York.

Goeritz ML, Bowers MR, Slepian B, Marder E (2013). Neuropilar projections of the anterior gastric receptor neuron in the stomatogastric ganglion of the Jonah crab, Cancer borealis. PLoS ONE. 8(12):e79306. [direct link]

Williams AH, Calkins A, O’Leary T, Symonds R, Marder E, Dickinson PS (2013). The neuromuscular transform of the lobster cardiac system explains the opposing effects of a neuromodulator on muscle output. J Neurosci. 33(42):16565-75. [pubmed]

Gutierrez GJ, Marder E (2013). Rectifying electrical synapses can affect the influence of synaptic modulation on output pattern robustness. J Neurosci 33(32):13238-48. [pubmed]

Gerhard F, Kispersky T, Gutierrez GJ, Marder E, Kramer M, Eden U (2013). Successful Reconstruction of a Physiological Circuit with Known Connectivity from Spiking Activity Alone. PLoS Comput Biol 9(7): e1003138. [link]

Katz P, Grillner S, Wilson R, Borst A, Greenspan R, Buzsáki G, Martin K, Marder E, Kristan W, Friedrich R, Chklovskii D (2013). Vertebrate versus invertebrate neural circuits. Curr Biol. 23(12):R504-6. [pubmed]

O’Leary T, Williams AH, Caplan JS, Marder E (2013). Correlations in ion channel expression emerge from homeostatic regulation mechanisms. Proc Natl Acad Sci USA. 110(28):E2645-54. [pubmed] [link]

Williams AH, Kwiatkoswki MA, Mortimer AL, Marder E, Zeeman ML, Dickinson PS (2013). Animal-to-animal variability in the phasing of the crustacean cardiac motor pattern: an experimental and computational analysis. J Neurophysiol. 109:2451-65. [pubmed]

Gutierrez GJ, O’Leary T, Marder E (2013). Multiple mechanisms switch an electrically coupled, synaptically inhibited neuron between competing rhythmic oscillators. Neuron 77(5): 845-858. pubmed

Rinberg A, Taylor AL, Marder E (2013). The effects of temperature on the stability of a neuronal oscillator. PLoS Comput Biol. 9(1):e1002857. direct link

Callaway EM, Marder E. (2012) Common Features of Diverse Circuits.  Current Opinion in Neurobiology 22: 565-567. pubmed

Kispersky T, Caplan J, Marder E (2012).
Increase in sodium conductance decreases firing rate and gain in model neurons. J. Neurosci., 32: 10995-1004. pubmed

Tang LS, Taylor AL, Rinberg A, Marder E (2012).
Robustness of a rhythmic circuit to short and long-term temperature
changes. J. Neurosci, 32(29):10075-85. pubmed

Brookings T, Grashow R, Marder E. (2012) Statistics of
neuronal identification with open and closed loop measures of
intrinsic excitability. Front. Neural Circuits 6:19. doi:
10.3389/fncir.2012.00019 pubmed

Szabo TM, Chen R, Goeritz M, Maloney RT, Tang LS, Li L, Marder E. (2011). Distribution and physiological effects of
B-type allatostatins in the stomatogastric nervous system of the crab,
Cancer borealis. J. Comp. Neurol., 519: 2658-2676. PMC3245975. pubmed

Kispersky T, Gutierrez G, Marder E. (2011). Functional
connectivity in a rhythmic inhibitory circuit using Granger causality.
Neural Systems & Circuits, 1:9. PMC3314404. pubmed

Marder E, Taylor AL. (2011) Multiple models to capture the
variability in biological neurons and networks. Nature Neuroscience,
14: 133–138. PMC2826985. pubmed

Tang LS, Goeritz M, Caplan J, Taylor AL, Fisek M, Marder, E. (2010) Precise temperature compensation of phase in a
rhythmic motor pattern. PLoS Biology, 8(8): e1000469.
doi:10.1371/journal.pbio.1000469. highlighted in a Synopsis.
PMC2930868 pubmed

Grashow R, Brookings T, Marder E. (2010) Compensation for
variable intrinsic neuronal excitability by circuit-synaptic
interactions. J. Neuroscience, 30: 9145 – 9156. PMC2913134 pubmed

Marder E. (2010) The Crustacean Stomatogastric Nervous System. In:
Handbook of Brain Circuits. Shepherd, G.M. and Grillner, S. eds.
Oxford University Press, New York. Chapter 40, pages 470-473.

Goaillard JM, Taylor AL, Pulver SR, Marder E. (2010) Slow
and persistent postinhibitory rebound acts as an intrinsic short-term
memory mechanism. J. Neuroscience, 30: 4687-4692. PMC2885135. pubmed

Tobin AE, Tang LS, Grashow RG, Pulver SR, Marder E.
(2009) Using the dynamic clamp to explore the relationship between
intrinsic activity and network dynamics. Destexhe, A., Bal, T. eds.
Dynamic Clamp. Springer Series in Computational Neuroscience 101. pdf

Goaillard JM, Taylor AL, Schulz D, Marder E. (2009)
Functional consequences of animal-to-animal variation in circuit
parameters. Nature Neuroscience, 12: 1424-1430. PMC2826985. pubmed

Ma M, Szabo TM, Jia C, Marder E, Li L (2009) Mass spectrometric characterization and physiological actions of the first crustacean C-type allatostatins. Peptides. 30(9):1660-8. pubmed

Tobin AE, Cruz-Bermudez ND, Marder E, Schulz DJ. (2009) Correlations in ion channel mRNA in rhythmically active neurons. PLoS One. 4(8):e6742. pubmed

Grashow R, Brookings T, Marder E. (2009) Reliable neuromodulation from circuits with variable underlying structure. Proc Natl Acad Sci U S A. 106(28):11742-6. pubmed

Grashow, R., Brookings, T. and Marder, E. (2009) Reliable
neuromodulation from circuits with variable underlying structure.
Proc Natl Acad Sci USA, 106: 11742-11746. PMC2701344 | Pubmed |

Taylor A.L, Goaillard J-M, Marder E. (2009) How multiple
conductances determine electrophysiological properties in a
multicompartmental model. J. Neuroscience, 29: 5573-5586;
doi:10.1523. PMC2821064. pubmed

Rehm KJ, Deeg KE, Marder E. (2008) Developmental regulation of neuromodulator function in the stomatogastric ganglion of the lobster, Homarus americanus. J Neurosci. 28(39):9828-39. pubmed

Rehm KJ, Taylor AL, Pulver SR, Marder E (2008) Spectral analyses reveal the presence of adult-like activity in the stomatogastric motor patterns of the embryonic lobster Homarus americanus. Journal of Neurophysiology. 99(6):3104-22. pubmed

Cape SS, Rehm KJ, Marder E, Li L (2008) Mass spectral comparison of the neuropeptide complement of the stomatogastric ganglion and brain in the adult and embryonic lobster, Homarus americanus. Journal of Neurochemistry, May; 105 (3): 690-702. pubmed

Schulz DJ, Goaillard JM, Marder EE.(2007) Quantitative expression profiling of identified neurons reveals cell-specific constraints on highly variable levels of gene expression. Proc Natl Acad Sci USA. 104(32):13187-91. pubmed

Cruz-Bermúdez ND, Marder E.(2007) Multiple modulators act on the cardiac ganglion of the crab, Cancer borealis. J Exp Biol. 210(Pt 16):2873-84. pubmed

Fu Q, Tang LS, Marder E, Li L. (2007) Mass spectrometric characterization and physiological actions of VPNDWAHFRGSWamide, a novel B type allatostatin in the crab, Cancer borealis. J Neurochem. 101(4):1099-107. pubmed

Bucher D, Johnson CD, Marder E. (2007) Neuronal morphology and neuropil structure in the stomatogastric ganglion of the lobster, Homarus americanus. J Comp Neurol, 501(2):185-205. pubmed

Marder E, Tobin AE, Grashow R. (2007) How tightly tuned are network parameters? Insight from computational and experimental studies in small rhythmic motor networks. Prog Brain Res 165:193-200. pubmed

Taylor AL, Hickey TJ, Prinz AA, Marder E. (2006) Structure and visualization of high-dimensional conductance spaces. J Neurophysiol, 96(2):891-905. pubmed

Marder E, Goaillard JM. (2006) Variability, compensation and homeostasis in neuron and network function. Nat Rev Neurosci, 7(7):563-74. pubmed

Goaillard JM, Marder E. (2006) Dynamic clamp analyses of cardiac, endocrine, and neural function. Physiology (Bethesda), 21:197-207. pubmed

Bucher D, Taylor AL, Marder E. (2006) Central pattern generating neurons simultaneously express fast and slow rhythmic activities in the stomatogastric ganglion. J Neurophysiol, 95(6):3617-32. pubmed

Billimoria CP, DiCaprio RA, Birmingham JT, Abbott LF, Marder E. (2006) Neuromodulation of spike-timing precision in sensory neurons. J Neurosci, 26(22):5910-9.pubmed

Cruz-Bermudez ND, Fu Q, Kutz-Naber KK, Christie AE, Li L, Marder E. (2006) Mass spectrometric characterization and physiological actions of GAHKNYLRFamide, a novel FMRFamide-like peptide from crabs of the genus Cancer. J Neurochem, 97(3):784-99.pubmed

Schulz DJ, Goaillard JM, Marder E. (2006) Variable channel expression in identified single and electrically coupled neurons in different animals. Nat Neurosci, 9(3):356-62.pubmed

Thirumalai V, Prinz AA, Johnson CD, Marder E. (2006) Red pigment concentrating hormone strongly enhances the strength of the feedback to the pyloric rhythm oscillator but has little effect on pyloric rhythm period. J Neurophysiol, 95(3):1762-70. pubmed

Bullock TH, Bennett MVL, Johnston D, Josephson R, Marder E, Fields RD. (2005) Neuroscience. The Neuron Doctrine, Redux. Science, 310(6749):791-793. pubmed

Billimoria CP, Li L, Marder E. (2005) Profiling of neuropeptides released at the stomatogastric ganglion of the crab, Cancer borealis with mass spectrometry. J Neurochem, 95(1):191-199. pubmed

Soto-Trevino C, Rabbah P, Marder E, Nadim F (2005) A computational model of electrically coupled, intrinsically distinct pacemaker neurons. J Neurophysiol, 94(1): 590-604. pubmed

Pulver SR, Bucher D, Simon DJ, Marder E (2005) Constant amplitude of postsynaptic responses for single presynaptic action potentials but not bursting input during growth of an identified neuromuscular junction in the lobster, Homarus americanus. J Neurobiol, 62:47-61. pubmed

Goaillard JM, Schulz DJ, Kilman VL, Marder E (2004) Octopamine modulates the axons of modulatory projection neurons. J Neurosci 24:7063-7073. pubmed

Mahadevan A, Lappe J, Rhyne RT, Cruz-Bermudez ND, Marder E, Goy MF (2004) Nitric oxide inhibits the rate and strength of cardiac contractions in the lobster Homarus americanus by acting on the cardiac ganglion. J Neurosci, 24:2813-2824. pubmed

Christie AE, Stein W, Quinlan JE, Beenhakker M, Marder E, Nusbaum MP (2004) Actions of a histaminergic/peptidergic projection neuron on rhythmic motor patterns in the stomatogastric nervous system of the crab, Cancer borealis. J Comp Neurol, 469:153-169.pubmed

Prinz AA, Billimoria CP, Marder E (2003) An alternative to hand-tuning conductance-based models: construction and analysis of databases of model neurons. J Neurophysiol 90:3998-4015. pubmed | database

Birmingham JT, Billimoria CP, DeKlotz TR, Stewart RA, Marder E (2003) Differential and history-dependent modulation of a stretch receptor in the stomatogastric system of the crab, Cancer borealis. J Neurophysiol 90: 3608 – 3616. pubmed

Li L, Kelley WP, Billimoria CP, Christie AE, Pulver SR, Sweedler JV, Marder E (2003) Mass spectrometric investigation of the neuropeptide complement and release in the pericardial organs of the crab, Cancer borealis. J Neurochem 87:642-656. pubmed

Luther JA, Robie AA, Yarotsky J, Reina C, Marder E, Golowasch J (2003) Episodic Bouts of Activity Accompany Recovery of Rhythmic Output by a Neuromodulator-and Activity-Deprived Adult Neural Network. J Neurophysiol 90:2720-2730. pubmed

Pulver SR, Thirumalai V, Richards KS, Marder E (2003) Dopamine and histamine in the developing stomatogastric system of the lobster Homarus americanus. J Comp Neurol 462:400-414. pubmed

Bucher D, Thirumalai V, Marder E (2003) Axonal dopamine receptors activate peripheral spike initiation in a stomatogastric motor neuron. J Neurosci 23:6866-6875.pubmed

Richards KS, Simon DJ, Pulver SR, Beltz BS, Marder E (2003) Serotonin in the developing stomatogastric system of the lobster, Homarus americanus. J Neurobiol 54:380-392. pubmed

Prinz AA, Thirumalai V, Marder E (2003) The functional consequences of changes in the strength and duration of synaptic inputs to oscillatory neurons. J Neurosci 23:943-954.pubmed

Pulver SR, Marder E (2002) Neuromodulatory complement of the pericardial organs in the embryonic lobster, Homarus americanus. J Comp Neurol 451:79-90. pubmed

Li L, Pulver SR, Kelley WP, Thirumalai V, Sweedler JV, Marder E (2002) Orcokinin peptides in developing and adult crustacean stomatogastric nervous systems and pericardial organs. J Comp Neurol 444:227-244. pubmed

Thirumalai V, Marder E (2002) Colocalized neuropeptides activate a central pattern generator by acting on different circuit targets. J Neurosci 22:1874-1882. pubmed

Golowasch J, Goldman MS, Abbott LF, Marder E (2002) Failure of averaging in the construction of a conductance-based neuron model. J Neurophysiol 87:1129-1131.pubmed

Gutovitz S, Birmingham JT, Luther JA, Simon DJ, Marder E (2001) GABA enhances transmission at an excitatory glutamatergic synapse. J Neurosci 21:5935-5943. pubmed

Goldman MS, Golowasch J, Marder E, Abbott LF (2001) Global structure, robustness, and modulation of neuronal models. J Neurosci 21:5229-5238. pubmed

Swensen AM, Marder E (2001) Modulators with convergent cellular actions elicit distinct circuit outputs. J Neurosci 21:4050-4058. pubmed

Nusbaum MP, Blitz DM, Swensen AM, Wood D, Marder E (2001) The roles of co-transmission in neural network modulation. Trends Neurosci 24:146-154. pubmed

Soto-Trevino C, Thoroughman KA, Marder E, Abbott LF (2001) Activity-dependent modification of inhibitory synapses in models of rhythmic neural networks. Nat Neurosci 4:297-303. pubmed

Swensen AM, Golowasch J, Christie AE, Coleman MJ, Nusbaum MP, Marder E (2000) GABA and responses to GABA in the stomatogastric ganglion of the crab Cancer borealis. J Exp Biol 203 Pt 14:2075-2092. pubmed

Birmingham JT, Szuts ZB, Abbott LF, Marder E (1999) Encoding of muscle movement on two time scales by a sensory neuron that switches between spiking and bursting modes. J Neurophysiol 82:2786-2797. pubmed

Golowasch J, Abbott LF, Marder E (1999) Activity-dependent regulation of potassium currents in an identified neuron of the stomatogastric ganglion of the crab Cancer borealis. J Neurosci 19:RC33. pubmed

Fenelon VS, Kilman V, Meyrand P, Marder E (1999) Sequential developmental acquisition of neuromodulatory inputs to a central pattern-generating network. J Comp Neurol 408:335-351. pubmed

Kilman V, Fenelon VS, Richards KS, Thirumalai V, Meyrand P, Marder E (1999) Sequential developmental acquisition of cotransmitters in identified sensory neurons of the stomatogastric nervous system of the lobsters, Homarus americanus and Homarus gammarus. J Comp Neurol 408:318-334. pubmed

Blitz DM, Christie AE, Coleman MJ, Norris BJ, Marder E, Nusbaum MP (1999) Different proctolin neurons elicit distinct motor patterns from a multifunctional neuronal network. J Neurosci 19:5449-5463. pubmed

Manor Y, Nadim F, Epstein S, Ritt J, Marder E, Kopell N (1999) Network oscillations generated by balancing graded asymmetric reciprocal inhibition in passive neurons. J Neurosci 19:2765-2779. pubmed